Undo Button for Cancer Cells

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In a revolutionary leap forward for cancer treatment, researchers at the Korea Advanced Institute of Science and Technology (KAIST) have unveiled a technology that could change the face of oncology. Led by Professor Kwang-Hyun Cho, the team has developed a method to transform colon cancer cells back into normal-like cells without destroying them.

Traditional cancer treatments often focus on eradicating cancer cells, which can lead to severe side effects and a high chance of recurrence. The KAIST researchers' approach, however, targets the root causes of cancer development, offering a potentially safer and more effective alternative.

The team's breakthrough hinges on the concept of reverting cancer cells to their normal state. By creating a digital twin of the gene network involved in cell differentiation, the researchers were able to identify master molecular switches that can steer cancer cells back to a normal-like state. This innovative technique was validated through various molecular experiments, cellular studies, and animal trials.

This discovery marks a significant departure from conventional cancer therapies, with the potential to minimize side effects and reduce the likelihood of cancer recurrence. While the study primarily focused on colon cancer, the principles behind this technology could be extended to other types of cancer as well.

The findings, published in the journal Advanced Science, pave the way for the development of reversible cancer therapies, offering new hope to patients worldwide. As this technology continues to evolve, it may redefine how we approach cancer treatment, making it safer and more effective.

Credit: Interesting Engineering on MSN
Story by Srishti Gupta

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